WormTSS: The Primary Transcriptome of C. elegans

Despite the fundamental importance of transcription start sites (TSSs), little is known about TSSs in C. elegans. This is due to the high frequency of trans-splicing of C. elegans mRNAs, a process which post-transcriptionally removes RNA segments of variable length from the 5'end of mature mRNAs. WormTSS is a comprehensive collection of TSSs for trans-spliced genes generated from the sequencing of Illumina reads from pre-trans-splicing 5'-ends that were captured using a modified 5'-SAGE procedure. Our data provides an enabling resource for both experimental and theoretical analysis of gene structure and function in C. elegans.

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